The Role of Gabapentin in The Treatment of Tinnitus

Authors

  • Yousef Watfa

Abstract

Tinnitus is considered one of the most common symptoms that urge the patient to visit the ENT doctors(otolaryngologists) it is also difficult to recognize exactly the main reason of tinnitus, which create a problem for the doctor  and for the patient as well.

A research has been conducted on " 50" patients by using Gabapentin for treating tinnitus in patients visited  private clinics and the ENT clinic in BaniasNathional Hospital during the period from 2012 to 2015.

Patients were given 200 mg Gabapentin orally every day,  after ensuring their tolerance of Gabapentin, the dose was increased by average 200 mg every two weeks until it reached 1600 mg. The dose 1600mg was divided into two doses in the morning and in the evening. The treatment lasted for six months.

We observed, that Gabapentin had positive effects for treating tinnitus to the patients who didn't have acoustic trauma or long term noise. Treatment with Gabapentin was more effective on young  people, and on who  had a short term tinnitus .

Therefore,we conclude that the use of Gabapentin in treating tinnitus is advisable because of its major inhibitory neurotransmitter and its wide distribution in thecentral auditory pathway.

دور الغابابنتين Gabapentin في معالجة الطنين

يعتبر الطنين أحد أشيع الأعراض التي يأتي بها المرضى الى طبيب الاذن والانف والحنجرةوالتي غالبا يصعب معرفة السبب المؤدي لها  وهذا يشكل مصدر قلق للمريض والطبيب .

تم اجراء البحث باستخدام عقار دوائي هو الغابابنتين في معالجة الطنين عند 50 مريضا من مراجعي العيادة الخاصة والعيادة الاذنية في الهيئة العامة لمشفى الشهيد اياد احمد ابراهيم ( بانياس الوطني سابقا) خلال الفترة
2012 م – 2015 م.تم اعطاء الغابابنتين بجرعة 200 ملغ يوميا فمويا, وبعد التأكد من التحمل الدوائي تم زيادة الجرعة بشكل تدريجي بمعدل 200ملغ كل اسبوعين, وبجرعة قصوي 1600 ملغ يومياً مقسمة على جرعتين صباحية ومسائية, واستمرت المعالجة لمدة ستة اشهر .

لوحظ وجود تأثيرات ايجابية في معالجة الطنين عند المرضى الذين لم يتعرضوا للرضوض الصوتية أو التأثير المديد للضجيج , وكانت الاستجابة للمعالجة افضل في الاعمار المبكرة وايضا كلما كانت الفترة الزمنية للطنين قصيرة, ولذا ينصح باستخدام الغابابنتين كدواء مثبط للنواقل العصبية في الطرق السمعية المركزية في معالجة الطنين.

Downloads

Published

2018-09-09

How to Cite

1.
Watfa Y. The Role of Gabapentin in The Treatment of Tinnitus. Tuj-hlth [Internet]. 2018Sep.9 [cited 2024Apr.19];39(3). Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/3868

Issue

Vol. 39 No. 3 (2017): العلوم الصحية

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.