Determining the Time Required to Achieve Peak Cycloplegic Effect of Cyclopentolate 1% in Children
Abstract
Purpose: To determine the time required to achieve peak cycloplegic effect of cyclopentolate 1% in children, and evaluate the correlation between this time and each of pupillary reaction, pupillary diameter and refractive status of the patient.
Patients and methods: This was an analytical cross-sectional study involving children aged 6 to 15 years with dark irides who were attending ophthalmology clinic in Tishreen University Hospital in Lattakia. Cyclopentolate 1% was installed three time at 10-minute intervals. The spherical equivalent, pupillary reaction, and pupillary diameter were recorded before the first drop and nine times after the last drop at 10-minute intervals. The time required to achieve peak cycloplegic effect was defined as the time point at which the spherical equivalent reached and remained within the equivalence limit (0.25 D) of the final value at 110 minutes.
Results: 58 children (116 eyes) were enrolled in this study. Their mean age was 9.8 years (range: 6-15 years). The time required to achieve peak cycloplegic effect was 40 minutes after the first drop of cyclopentolate. A poor correlation was observed between the time of peak cycloplegic effect and the pupillary reaction ( r= 0.03). And the peak cycloplegic effect was reached earlier than the maximum pupillary dilatation.
Conclusion: In most children, the peak cycloplegic effect of cyclopentolate was 40 minutes after the first instillation. The absence of a pupillary reaction or the maximum pupillary dilatation should not be used as an indicator of maximum cycloplegia.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series
Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in Tishreen University Journal for Research and Scientific Studies - Health Sciences Series . The Readers have the right to send, print and subscribe to the initial version of the article, and the title of Tishreen University Journal for Research and Scientific Studies - Health Sciences Series Publisher
journal uses a CC BY-NC-SA license which mean
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
- The licensor cannot revoke these freedoms as long as you follow the license terms.
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
