Synthesis and Theoretical Study of new N-(3-methyl 5-isothiazolyl) maleimide derivativs

Authors

  • Shahid Moustapha
  • Emad Hwije
  • Hadeel Mosalem

Abstract

 

New derivative N-(3-methyl, 5-isothiazolyl) maleimide have been Synthesized via Diels- Alder Reaction between maleimide with each of furan and 2,3-di methyl butadiene.

The structure of synthesized compound have been established on the basic of their spectral (IR, 1HNMR, elemental analysis) data. Maleimide was treated with furan to give two isomers were (endo),(exo).

The proportion of each isomer has been different dependence reaction temperature.

The thermodynamic properties of reaction have been determined using the theoretical Methods CBS-4m, B3PW91,  MPW1PBE and MPW1PW91.

The all theoretical methods  results have been accorded with the experimental method results .

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Published

2019-02-27

How to Cite

1.
Moustapha S, Hwije E, Mosalem H. Synthesis and Theoretical Study of new N-(3-methyl 5-isothiazolyl) maleimide derivativs. TUJ-BA [Internet]. 2019Feb.27 [cited 2024May2];39(3). Available from: https://journal.tishreen.edu.sy/index.php/bassnc/article/view/3744

Issue

Vol. 39 No. 3 (2017): العلوم الأساسية

Section

Articles

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