طريقة كروماتوغرافية جديدة لفصل الأوميبرازول عن نواتج تخربه وتحديده كمياً في مستحضراته الدوائية

Authors

  • مروان توما
  • منان سليمان
  • أنس رجب

Abstract

تم تطوير طريقة كروماتوغرافية جديدة من أجل التحديد الكمي للأوميبرازول في مستحضراته الدوائية وإظهار كل من الأوميبرازول ونواتج تخربه منفصلة في كروماتوغرام واحد, وذلك باستخدام تقانة الكروماتوغرافية السائلة عالية الأداء HPLC.

تم التحقق من صحة هذه الطريقة Validation بإجراء اختبارات الصحة والدقة والمجال والخطية والانتقائية/النوعية, ثم حسب كل من حد الكشف  LODوالحد الكمي LOQ .

New chromatographic method for Quantitative Determination of Omeprazole in its Pharmaceutical Products was produced. Omeprazole and its degradation components were well separated in same chromatogram by using by using high perfume liquid chromatography (HPLC).

The new analytical method has been validated by these characteristic tests (accuracy, precision, range, linearity, specificity/selectivity, limit of detection (LOD) and limit of quantitative (LOQ) ).

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Published

2018-12-06

How to Cite

1.
توما م, سليمان م, رجب أ. طريقة كروماتوغرافية جديدة لفصل الأوميبرازول عن نواتج تخربه وتحديده كمياً في مستحضراته الدوائية. TUJ-BA [Internet]. 2018Dec.6 [cited 2024May13];32(1). Available from: https://journal.tishreen.edu.sy/index.php/bassnc/article/view/5160

Issue

Vol. 32 No. 1 (2010): العلوم الأساسية

Section

Articles

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