Preparation and Characterization of New Ion Selective Electrode for Determination of Vitamin B6

Authors

  • Hiba Nasser Tishreen University
  • Hajar Nasser Tishreen University

Abstract

A simple and rapid electrochemical sensor has been developed to determine the concentration of pyridoxine chloride (vitamin B6). This method is based on the ion-association complex of the pyridoxine hydrochloride with cobalt chloride as ion pair in paste carbon electrode, and paraffin oil as a plasticizer.

 

The electrode shows a Nernstian response within a range of concentrations (1×10-6-1×10-2) mol/L within a temperature range of (20-40)0C and a pH range of pH(2-4). It gave a Nernstian slope of 56.206±2mv/decade, a response time of 45sec, and a detection limit of 1.79×10-6 mol/L. It was also shown by calculating selectivity coefficients using Matched potential method that the proposed electrode shows high selectivity for vitamin B6 in the presence of a number of interfering ions..

The concentration of vitamin B6 in some pharmaceutical preparations was determined using the proposed method, giving a recovery of 100.9% and 101.8%. Comparison was also made with a reference method, and it was noted that there was good agreement in the results between the two methods, Therefore, this selective electrode can be adopted as a potential method for determining vitamin B6.

 

 

 

Keywords: pyridoxine hydrochloride, paste carbon electrode, pharmaceutical preparations.

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Published

2024-12-22

How to Cite

1.
ناصر ه, هاجر ناصر. Preparation and Characterization of New Ion Selective Electrode for Determination of Vitamin B6. TUJ-BA [Internet]. 2024Dec.22 [cited 2024Dec.23];46(4):121-36. Available from: https://journal.tishreen.edu.sy/index.php/bassnc/article/view/17366

Issue

Vol. 46 No. 4 (2024): Tishreen University Journal of Research and Scientific Studies - Basic Sciences Series

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Articles

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