Preparation and Characterization of New Ion Selective Electrode for Determination of Vitamin B6

Authors

  • Hiba Nasser Tishreen University
  • Hajar Nasser Tishreen University

Abstract

A simple and rapid electrochemical sensor has been developed to determine the concentration of pyridoxine chloride (vitamin B6). This method is based on the ion-association complex of the pyridoxine hydrochloride with cobalt chloride as ion pair in paste carbon electrode, and paraffin oil as a plasticizer.

 

The electrode shows a Nernstian response within a range of concentrations (1×10-6-1×10-2) mol/L within a temperature range of (20-40)0C and a pH range of pH(2-4). It gave a Nernstian slope of 56.206±2mv/decade, a response time of 45sec, and a detection limit of 1.79×10-6 mol/L. It was also shown by calculating selectivity coefficients using Matched potential method that the proposed electrode shows high selectivity for vitamin B6 in the presence of a number of interfering ions..

The concentration of vitamin B6 in some pharmaceutical preparations was determined using the proposed method, giving a recovery of 100.9% and 101.8%. Comparison was also made with a reference method, and it was noted that there was good agreement in the results between the two methods, Therefore, this selective electrode can be adopted as a potential method for determining vitamin B6.

 

 

 

Keywords: pyridoxine hydrochloride, paste carbon electrode, pharmaceutical preparations.

Downloads

Published

2024-12-22

How to Cite

1.
ناصر ه, هاجر ناصر. Preparation and Characterization of New Ion Selective Electrode for Determination of Vitamin B6. TUJ-BA [Internet]. 2024Dec.22 [cited 2025Apr.3];46(4):121-36. Available from: https://journal.tishreen.edu.sy/index.php/bassnc/article/view/17366

Issue

Vol. 46 No. 4 (2024): Tishreen University Journal of Research and Scientific Studies - Basic Sciences Series

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to the Tishreen University Journal -Basic Sciences Series  

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in Tishreen University Journal -Basic Sciences Series .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of Tishreen University Journal -Basic Sciences Series   Publisher

 

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.