Renal Cell Carcinoma: Correlation of Multislice Computed Tomography Imaging (MSCT) Features and Pathologic Findings

Abstract

Background and objectives: CT has an important role in detecting Renal cell carcinoma and differentiating it from other focal renal lesions, in addition to its importance in detecting secondary metastasis, staging the tumor, and investigating tumor recurrence after treatment. Renal cell carcinoma is the most common (85%) of all malignant renal tumors. Renal cell carcinoma is a common cause of death worldwide, so early and accurate diagnosis contributes to early and appropriate treatment. The purpose of the study correlates Multislice Computed Tomography Imaging findings with pathology results.

Subjects and Methods: This was an analytic study, included 63 patients (76% male, 24% female) in Tishreen University Hospital, Lattakia, Syria. Patients underwent Multislice Computed Tomography MSCT scan and comparison with pathology results.

Results: We found solid soft tissue mass (85%), cystic mass (15%), with heterogeneous enhancement. We detect calcification in 14%, local renal enlargement in 98%, deformity of renal countor in 95%, deformity of renal sinus and collecting system in 23%.. No fatty tissue density seen in all cases. In comparison with pathology MSCT has 10% false negative results in the diagnosis of renal vein involvement, 14% false positive resuls in the diagnosis of perinephric fat tissue involvement, and 4% false negative results in the diagnosis of Gerota's fascia involvement, and 1,5% false negative results in the diagnosis of adrenal involvement.