Efficiency of narrow band ultraviolet B in treatment of refractory renal pruritus among patients on hemodialysis
Abstract
Objective: Evaluate the efficacy of narrowband ultraviolet B (nb-UVB) phototherapy in the treatment of refractory renal pruritus among patients on hemodialysis.
Methods: The study enrolled 35 patients suffering from chronic renal disease and undergoing hemodialysis, who experienced severe pruritus nonresponsive to conventional treatments. These patients were treated with nb-UVB phototherapy 3 times a week for 4 months. Pruritus was evaluated monthly during treatment, and 3 months after the end of treatment using 12-item of pruritus severity scale (12-PSS).
Results: There was a significant improvement in the severity of itching after the first three months of nb-UVB phototherapy, but the improvement at the fourth visit was not satisfactory. The mean 12-PSS value decreased from 19.6 ±1.8 before the treatment to 9.4 ±3.8 at the end of the treatment (p-value <0.001), but increased to 12.6 ±3.9 after 3 months after the end treatment. The total response rate was 82.9%. Although the recurrence rate was 44.8%, the overall improvement was significant compared to the condition before treatment (p-value <0.001). Conclusion: The treatment of nb-UVB phototherapy for refractory renal pruritus in dialysis patients is effective, beneficial and safe even if a complete response is not achieved.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series
Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in Tishreen University Journal for Research and Scientific Studies - Health Sciences Series . The Readers have the right to send, print and subscribe to the initial version of the article, and the title of Tishreen University Journal for Research and Scientific Studies - Health Sciences Series Publisher
journal uses a CC BY-NC-SA license which mean
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
- The licensor cannot revoke these freedoms as long as you follow the license terms.
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
- ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.