Correlation of Red Blood cell Parameters and glycemic control in Type 2 Diabetes Mellitus patients

Authors

  • Haia Waridah Tishreen University
  • Rose Said Tishreen University
  • Atia Khamis Tishreen University

Abstract

Background: Diabetes Mellitus Type 2 (T2DM) is a worldwide metabolic disorder characterized by persistent hyperglycemia and increased risk of microvascular and macrovascular complications that affect patients quality of life. The main concern of physicians is glycemic control. Consistent hyperglycemia causes functional and structural changes of red blood cells which may reflect on its parameters.

Objective: Poor glycemic control is associated with high risk of developing diabetic microvascular complications. The main aim of this study is determining the RBCs parameters and their correlation to diabetic control, so we can evaluate the glycemic state and the risk of developing microvascular complications depending on these parameters.

Methods: The study included 130 T2DM patients and 30 healthy control.HbA1, CRP, RBCs, Hct, Hb, MCV, MCH, MCHC and RDW were measured in these patients. The study was conducted from January 2021 to December 2021 in Tishreen University Hospital and Diabetic Center.

Results: Red cell distribution width (RDW) was significantly higher in diabetic patients than in control subjects (P<0.001). It was also higher in patients with uncontrolled glycemia (HbA1c>7%) than those with good control (HbA1c ≤7%,P<0.001)

Conclusion: RDW has recently been studied in many diseases. RDW is significantly higher in diabetic patients than healthy subjects and is particularly higher in uncontrolled glycemia and in patients with diabetic microvascular complications.

 

KEY WORDS: Glycated Hemoglobin HbA1C ,Red blood cell Distribution Width RDW, C-Reactive Protein CRP ,Diabetes Mellitus.

Downloads

Published

2023-03-01

How to Cite

1.
وريده ه, روز سعيد, عطية خميس. Correlation of Red Blood cell Parameters and glycemic control in Type 2 Diabetes Mellitus patients. Tuj-hlth [Internet]. 2023Mar.1 [cited 2024Nov.24];44(6):391-40. Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/13624

Issue

Vol. 44 No. 6 (2022): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

Section

Master student researches

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.