Evaluation role of Serum uric acid to creatinine ratio as a useful predictor of renal dysfunction among diabetic patients type 2

Authors

  • ali subh Tishreen University
  • Remal Abdulaziz Asaad Tishreen University

Abstract

Objective: To study the presence of a relationship between the serum uric acid / creatinine ratio (SUA/Cr) and annual eGFR decline rate to predict kidney damage incidence among patients with T2DM.

Study design: This study was conducted on 118 adults with type 2 diabetes mellitus at Tishreen University Hospital and Diabetes Care Center in Latakia / Syria. The study form was filled out after the patients 'acceptance. HbA1c,  uric acid, Creatinine, fasting blood glucose, and lipid profile were measured for patients. We calculated the initial SUA/Cr (from which the patients were divided according to this ratio into 4 groups), eGFR (beginning and after 6 months), and annual eGFR decline rate.  We studied the existence of a relationship between SUA/Cr and the annual eGFR decline rate, and  SUA/Cr with each of : systolic and diastolic blood pressure, BMI, waist circumference, sex, duration of diabetes, lipid formula, HbA1c, and fasting blood glucose.

Results:

The results obtained showed a statistically significant positive correlation between the annual eGFR decline rate and the uric acid/creatinine ratio (r=0.34, p=0.01), a statistically significant positive correlation between uric acid/creatinine ratio and waist circumference (r=0.38, p=0.001), a statistically significant negative correlation between the uric acid/creatinine ratio and both HbA1c (r = -0.30, p = 0.001) and fasting blood glucose in patients (r = -0.36, p = 0.00), But There were no statistically significant differences between the groups and each of: systolic and diastolic blood pressure, BMI, duration of diabetes, lipid formula, sex.

Downloads

Published

2023-03-27

How to Cite

1.
صبح ع, رمال عبد العزيز أسعد. Evaluation role of Serum uric acid to creatinine ratio as a useful predictor of renal dysfunction among diabetic patients type 2. Tuj-hlth [Internet]. 2023Mar.27 [cited 2024Dec.26];45(1):383-97. Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/14412

Issue

Vol. 45 No. 1 (2023): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

Section

Master student researches

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.