Study of Escherichia coli antimicrobial resistance in lower urinary tract infections in women

Authors

  • Suzan Samra Tishreen University
  • Hassan Nasser Tishreen University
  • Riham Nasser Tishreen University

Abstract

Urinary tract infection (UTI) is one of the most frequent bacterial infections among females. This study was designed to determine the prevalence of Escherichia coli, as causing agent for UTIs, in women, and to assess the susceptibility of clinically prescribed antibiotics, in treating UTIs. For this purpose, urine samples from 240 non-pregnant outpatient women were collected, at Tishreen University Hospital, in Lattakia, Syria, between 1/1/2020 and 10/30/2020. All patients had symptoms of lower urinary infection, but no urinary tract abnormalities, or obstructive urinary problems (urinary stones or catheters(.

The study results showed that 53.84% of UTIs were caused by  Escherichia coli, and the most effective antibiotics against the isolated strains were carbapenems (ertapenem, imipenem), piperacillin + tazobactam with an effectiveness of up to 100%, followed by meropenem, colistin, amikacin, with an efficiency that exceeded 90% (96%, 95%, 90%, respectively), then nitrofurantoin, amoxicillin with clavulanic acid (84%, 80%, respectively). Whereas the resistance percentages of the isolated Escherichia coli against ciprofloxacin, levofloxacin, and cefixime were 35.3%, 36.4%, and 56.23%, respectively). Our results concluded the importance of conducting antibiotic susceptibility tests before prescribing antibiotics for UTIs-treatment.

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Published

2023-05-18

How to Cite

1.
سوزان سمرة, حسان ناصر, رهام ناصر. Study of Escherichia coli antimicrobial resistance in lower urinary tract infections in women. Tuj-hlth [Internet]. 2023May18 [cited 2024Dec.26];45(2):325-37. Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/15075

Issue

Vol. 45 No. 2 (2023): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

Section

Master student researches

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