Bacterial study of some eye drops products and lens sterilizing solutions sold in Syria

Authors

  • Rana Hseno Tishreen University
  • Mouna Morie Tishreen University

Abstract

Medications instilled directly into the eye are expected to be sterile throughout use.  It must also be filed and properly packaged.  Recent studies have documented an increase in the incidence of microbial contamination associated with the use of bacteriologically contaminated lens and lens sterilization solutions and eye drops.[1,2,3]

This study aims to evaluate the presence of bacterial contamination in multi-dose eye drops and contact lens sterilization solutions marketed in Syria.

 A total of 75 samples were studied, including 55 eye drops offered for sale in pharmacies in the city of Lattakia, containing active substances with different physiological effects.  Also, 20 sterilization solutions for contact lenses offered for sale in pharmacies and cosmetic stores were studied in terms of their bacteriological quality upon opening directly, and the possibility of contamination of these solutions during use for 15 days and 30 days, respectively.  Bacterial contamination rates and resulting bacterial species were determined by available methods in the Bacteriological Laboratory, Tishreen University Hospital.  A sensitivity test for antibiotics for specific germs was also conducted to find out the degree of pathogenicity and severity of these germs.

 The results of bacterial culture showed the growth of bacteria in 2.80% of the total number of samples (2 out of 75) when cultured immediately after opening and incubated under appropriate conditions.

 As for the percentage of samples contaminated with bacteria after 15 days of opening, it was 16.36% of the total number.

 The percentage of bacterially contaminated samples increased to 24% after 30 days of opening, and lens sterilization solutions accounted for 61.9% of them.

 Most of the identified bacteria were Escherichia coli, Enterobacter, hemolytic streptococci and non-hemolytic streptococci.

 The resulting bacteria were resistant to a significant percentage of the broad spectrum antibiotics tested.

Downloads

Published

2023-12-03

How to Cite

1.
حسينو ر, مرعي م. Bacterial study of some eye drops products and lens sterilizing solutions sold in Syria. Tuj-hlth [Internet]. 2023Dec.3 [cited 2024Nov.28];45(5):429-37. Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/15540

Issue

Vol. 45 No. 5 (2023): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

Section

Master student researches

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.