Early Oral Refeeding In Patients With Mild Acute Pancreatitis
Abstract
Background: Acute pancreatitis is the most common inpatient gastrointestinal diagnosis in the United States. 80% of acute pancreatitis cases were classified as mild in severity and resolved within 5-7 days. the optimal timing for recommencing oral feeding is still controversial.
Aim: To evaluate the safety and efficacy of early oral refeeding (EOR) in patients with mild acute pancreatitis (AP).
Materials and Methods: This was a prospective, randomized, comparative study conducted in the department of gastroenterology in Tishreen University Hospital in 2022-2023 years. A total of (96) patients who suffer from mild acute pancreatitis. They were splited randomly into two groups, 48 patients in early oral refeeding group (EOR) (started oral feeding once they subjectively felt hungry) and 48 patients in Late (regular) oral refeeding group (LOR). Patients of the two groups were compared for abdominal pain relapse, serum amylase elevation after oral refeeding and total length of hospitalization (LOH).
Results: There were 48 patients in each group, There was no significant statistical differences when comparing abdominal pain relapse and serum amylase elevation after oral refeeding between the two groups which shows good tolerance for early oral refeeding. patients in the EOR group had significantly shorter total length of hospitalization (LOH) (3.61 ± 0.57 vs 5.81 ± 0.77 days; P˂ 0.05) than LOR group.
Conclusion: In patients with mild acute pancreatitis, early oral refeeding (EOR), with the subjective feeling of hunger, is safe, efficient, and reduces LOH.
Keywords: refeeding in acute pancreatitis, early oral refeeding.
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