النزف الهضمي العلوي المحرض بمضادات الالتهاب غير القشرية
Abstract
ـ إن أهداف هذه الدراسة هي تقويم دور مضادات الالتهاب غير القشرية في تحريض النزيف الهضمي العلوي وعلى إمراضيته وخطر الموت المتعلق به، ومعرفة عوامل الخطورة لمن يعاني منه.
ـ كذلك معرفة إن كان الأطباء واصفو هذه العقاقير يأخذون على محمل الجد الاحتياطات اللازمة لمنع
أو التقليل من حدوث هذا النزيف المعدي عبر إعطاء مرضاهم مثبطات مضخة البروتون أو حتى عقاقير COX2 في حال كان المرضى بوضع حرج.
ـ تابعنا 50مريضاً تتراوح أعمارهم بين20 ـ79 سنة، دخلوا مشفى الأسد الجامعي باللاذقية بسبب نزيف هضمي علوي مع قيء دموي أو تغوط زفتي تالٍ لاستخدام مضادات الالتهاب غير القشرية في الفترة الممتدة بين1/9/2007 و 1 / 12 / 2008
ـ وتبين بالدراسة أن القرحة الاثني عشرية والمعدية من أهم أسباب النزيف، وتأكَّد ذلك بوساطة التنظير الهضمي.
The aim of this prospective follow – up study was to evaluate the effect of NSAIDs on upper gastrointestinal bleeding, morbidity, mortality and other risk factors in these patients. It also seeks to establish whether the NSAIDs – prescribing physicians take precautions to prevent or reduce ulceration by giving proton pump inhibitors ( PPIs ) or choose COX2 selective drugs in high risk group of patients.
50 patients whose ages are (20 – 79) years admitted to Alassad University Hospital in Lattakia between 1 / 9 / 2007 – 1 / 12 / 2008 with (VGIB) hematemesis or melena ofter use of NSAIDS.
The study shows that duodenal ulcer and gastric ulcer can be confirmed as the source of bleeding by endoscopy.
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