The relationship between lactate dehydrogenase (LDH) level in blood and the duration of transient tachypnea of the newborn.
Abstract
Objective: Transient tachypnea of the newborn TTNB is a common cause of respiratory distress in postnatal period. Although TTNB is a self-limited condition in most times , there are rare cases of more serious complications. We cannot predict the course of the case since the earlier hours of hospitalization , so this study importance is to investigate the relationship between LDH level in blood and the course of TTNB (the duration of hospitalization , and the incidence of complications).
Material and methods: The study included 120 infants with TTNB which was diagnosed clinically and on the basis of laboratory and chest-x rays results, patients were divided into two subgroups: the first one included infants with a normal LDH level in blood, and the other one included infants with a high LDH level in blood, the duration of hospitalization and the incidence of complications were compared between the two groups.
Results: The duration of hospitalization in infants with a high LDH level is longer than the duration of hospitalization in infants with a normal LDH level, and the duration of hospitalization increases as the value of LDH increases. The incidence of complications in infants with a high LDH level is more than the incidence of complications in infants with a normal LDH level, and the frequency of complications increases as the value of LDH increases.
Conclusions: There is a positive correlation between the LDH level in blood and the duration of hospitalization and the incidence of complications in infants with TTNB
هدف الدراسة :
تعتبر الـزلة التنفسية العابرة عند الوليد (TTNB (Transient tachypnea of the newborn سبباً شائعاً للاضطراب التنفسي عند الولدان بفترة بعد الولادة ، وعلى الرغم من أن الـ TTNBحدثية محددة لذاتها بأغلب الأحيان إلا أنه هناك حالات نادرة لاختلاطات أخطر، وبما أننا لا نستطيع التنبؤ بسير الإصابة منذ الساعات الأولى للاستشفاء تأتي أهمية الدراسة في تقييم العلاقة بين مستوى الـ LDH(Lactate dehydrogenase) في الدم مع تطور الزلة التنفسية العابرة عند الولدان (مدة الاستشفاء _حدوث الاختلاطات ).
المواد و الطرائق :
شملت الدراسة 120 وليداً تم استشفاؤهم باستطباب زلة تنفسية عابرة TTNB مشخصة سريرياً ومخبرياً وشعاعياً ، تم تقسيمهم إلى مجموعتين : الأولى (ولدان قيمة LDH الدم لديهم طبيعية ) والثانية (ولدان قيمة LDH الدم لديهم مرتفعة) وتمت مقارنة مدة الاستشفاء وحدوث الاختلاطات بين المجموعتين.
النتائج :
مدة الاستشفاء عند الولدان مع معدل LDH فوق الطبيعي هي أطول من مدة استشفاء الولدان مع معدل LDH طبيعي ، مع ازدياد مدة الاستشفاء كلما كانت قيمة LDH الدم أعلى ، والاختلاطات عند الولدان مع معدل LDH فوق الطبيعي هي أكبر منها عند الولدان مع معدل LDH طبيعي ، ويزداد تواتر حدوث الاختلاطات مع ارتفاع قيمة LDH الدم عند الولدان.
الاستنتاجات :
توجد علاقة إيجابية بين مستوى LDH الدم مع مدة الاستشفاء عند ولدان الزلة التنفسية العابرة وكذلك مع حدوث الاختلاطات عنهم
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