The Role of Mean Platelet Volume in the Exacerbation of Chronic Obstructive Pulmonary Disease

Authors

  • Malek Hijazie Tishreen Journal
  • Firas Al-Husein
  • Dima Fatahi

Abstract

Background: Studies have supported the correlation between mean platelet volume and COPD. However, there are limited data on the relationship between COPD exacerbation and mean platelet volume.

Aim: This study was aimed to evaluate the mean platelet volume trend in patients with COPD exacerbation.

Materials and Methods: This was a prospective study in which 80 patients with acute COPD exacerbation were enrolled at Tishreen University Hospital, Lattakia during the period between 2020 - 2019. The levels of mean platelet volume, C-reactive protein, complete blood count, and percent of predicted FEV1 were measured in subjects at admission (exacerbation period) and after 3 months (stable period).

Results: Subjects in the exacerbation period had significantly higher levels of C-reactive protein (P<0.0001), white blood cell count (P<0.0001) and percentage of neutrophils (P<0.0001) and lower percent-of-predicted FEV1 than in the stable period (P<0.0001).

Mean platelet volume levels were significantly decreased in the exacerbation period (P<0.0001).

Mean platelet volume levels correlated significantly with increase of C-reactive protein level in the exacerbation period (r = -0.342, p<0.001) and in the stable period (r = -0.168, p=0.0347).

Conclusion: Mean platelet volume may be an inflammatory marker in exacerbation of COPD.

Downloads

Published

2020-10-01

How to Cite

1.
حجازية م, الحسين ف, فتاحي د. The Role of Mean Platelet Volume in the Exacerbation of Chronic Obstructive Pulmonary Disease. Tuj-hlth [Internet]. 2020Oct.1 [cited 2024Nov.24];42(4). Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/9869

Issue

Vol. 42 No. 4 (2020): Tishreen University Journal for Research and Scientific Studies - Medical Sciences Series

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.