Association between the levels of blood platelet indicators and the severity of knee osteoarthritis (radiologic and clinical)

Authors

  • kasser Aldaw Tishreen University
  • Youssef Zreik Tishreen University
  • Areej Haifa Tishreen University

Abstract

 Objective:This study aims to investigate the relationship between platelet indices, and radiological and clinical disease severity in patients with primary osteoarthritis of the knee

Methods: Analytic study (Corss-secctional), the research sample included 83 patients (24 males, 59 females) with primary osteoarthritis in the knee joint, the ages of the research sample patients ranged between 40 to 60 years, a detailed history was taken for each patient, and a comprehensive clinical examination of active and passive joint movements was performed with clinical assessment according to the clinical Western Ontario and MacMaster Universities score (WOMAC), and the weight and height of each patient were measured, BMI (kg/m2) was calculated, as well as a complete blood count (CBC), sedimentation rate (ESR), and C protein Reactive (CRP), a simple radiograph of the knee joints anterior to posterior and lateral and the determination of the Kellgren-Lawrence score (K-L) were performed,

Results: The results showed that about two thirds of the study sample had mild to moderate OA according to WOMAC clinical assessment index and KL radiographic index. We note that there is a significant statistical relationship between BMI and WOMAC index and K-L index, which was higher in the severe group. We note significant differences for MPV between the two groups of patients as per radiographic evaluation which were higher in the severe group. It was noticed that there is a statistically significant increase for MPV between the two groups of patients according to their radiological assessment in the severe group, according to the different values of fields` BMI. It wasn't observed a statistically significant relationship between other platelet indices and the radiological and clinical severity of osteoarthritis in the knee joint according to the demographic factor.

Conclusion: Mean platelet volume (MPV) maybe considered as an important indices of the radiological progression of primary osteoarthritis of the knee joint.

Author Biographies

kasser Aldaw , Tishreen University

Assistant Professor,  departmemt of rheumatology, faculty of medicine

Youssef Zreik, Tishreen University

Assistant Professor, department of laboratory medicine, faculty of medicine

Areej Haifa, Tishreen University

Assistant Professor, department of laboratory medicine, faculty of medicine

Downloads

Published

2022-03-29

How to Cite

1.
الدو ك, زريق ي, هيفا أ. Association between the levels of blood platelet indicators and the severity of knee osteoarthritis (radiologic and clinical). Tuj-hlth [Internet]. 2022Mar.29 [cited 2024Nov.24];44(1):313-26. Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/12024

Issue

Vol. 44 No. 1 (2022): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

Section

Master student researches

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

Most read articles by the same author(s)