Evaluation the salivary zinc assay as a potential diagnostic tool in potential malignant lesions of oral cavity

Authors

  • Samira Zraiki
  • Muhammed Imad Khayat
  • Marwa Mohammad Khalil

Abstract

Salivary analysis, a non-invasive alternative to serum analysis, is an effective modality for diagnosis and for prognosis prediction of various diseases like oral cancer and even oral potentially malignant disorders. The aim of this study was to evaluate the level of zinc (Zn) in saliva of patients with oral leukoplakia (OL) and to compare the values with healthy controls. The study group comprised of15  clinically diagnosed and histopathologically confirmed cases of OL and 15 healthy controls matched in age and gender. The data were assessed statistically using SPSS.

It  was observed a slight decrease in OL patients(151.73 ±11.37 )compared with controls (156.13±10.12).However ,it was statistically insignificant  (P>0.05).

Further research is needed in this line in patients with oral potential malignant disorders with higher sample size in order to correlate habit and diet pattern which may affect the Zn status.

تحليل اللعاب هو بديل غير باضع للنسج كما أنه وسيلة فعالة لتشخيص والتنبؤ بإنذار العديد من الأمراض مثل سرطان الفم والآفات محتملة الخباثة .هدف هذه الدراسة تقييم مستويات الزنك في اللعاب لدى مرضى الطلاوة الفموية ومقارنة هذه القيم مع المجموعة الضابطة . مجموعة الدراسة ضمت 15 حالة طلاوة مشخصة سريرياً ونسيجياً و15 من الضوابط المطابقة في العمر والجنس . المعطيات قيمت إحصائياً باستخدام برنامج التحليل الإحصائي SPSS.كان هناك انخفاض في مستويات الزنك 151.73 ±11.37 عند مرضى الطلاوة مقارنة بالمجموعة الضابطة التي أظهرت مستويات أعلى 156.13±10.12ولكن هذا الانخفاض ليس ذو دلالة إحصائياً حيث (P>0.05).هناك حاجة إلى مزيد من البحث في هذا المجال في المرضى الذين يعانون من آفات فموية محتملة الخباثة بحجم عينة أكبر بهدف ربط نمط التغذية و العادات التي يمكن أن تؤثر على حالة الزنك .

Downloads

Published

2020-03-05

How to Cite

1.
Zraiki S, Khayat MI, Khalil MM. Evaluation the salivary zinc assay as a potential diagnostic tool in potential malignant lesions of oral cavity. Tuj-hlth [Internet]. 2020Mar.5 [cited 2024Apr.25];42(1). Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/9499

Issue

Vol. 42 No. 1 (2020): Medical Sciences Series

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.