Sensitivity and Specifity of Anorectal Manometry to Diagnose Hirschsprung Disease in Children with Chronic Constipation

Authors

  • Wajih Ali Tishreen University
  • Zuher Alshehabi Tishreen University
  • Ali Ibrahim Tishreen University
  • Aras Abdo Tishreen University

Abstract

Aim of study: evaluating the role of anorectal manometry in diagnosing Hirschsprung Disease to reduce reliance on rectal biopsy procedure.

Methods: during years 2019-2020 a prospective study conducted on 49 children suffering from chronic constipation with one or more of these characteristics (abdominal distention– history of delaying meconium– enema depend– hard stool– pain bowel movements), as these patients underwent the test, depending on presence or absence of rectoanal inhibitory reflex, patients underwent conservative treatment or rectal biopsy procedure.  

Results: Reflex was present in 40 patients. Rectal biopsies of 9 patients who were negative reflex were normal in 3, aganglionec in 6. Sensitivity, specificity, positive predictive value, negative predictive value of manometry test were 100%, 66%, 93%, 100% respectively.

Conclusion: ARM is an effective and safe tool. With high sensitivity and negative predictive value of manometry test, there is no need for rectal biopsy when test is normal. 

Author Biographies

Wajih Ali, Tishreen University

Associate Professor , surgery department

Zuher Alshehabi, Tishreen University

Professor ,  Pathology department

Ali Ibrahim, Tishreen University

Professor - Department of Pediatrics - Faculty of Human Medicine

Aras Abdo, Tishreen University

Postgraduate student , surgery department

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Published

2021-07-05

How to Cite

1.
علي و, الشهابي ز, ابراهيم ع, عبدو آ. Sensitivity and Specifity of Anorectal Manometry to Diagnose Hirschsprung Disease in Children with Chronic Constipation. Tuj-hlth [Internet]. 2021Jul.5 [cited 2024Nov.24];43(3). Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/10649

Issue

Vol. 43 No. 3 (2021): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

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