The Hypo-fractionated Radiotherapy in the Management of Pigmented Villonodular Synovitis. One center experience .

Authors

  • بسام سعد جامعة تشرين

Abstract

This article reviews our 6 years experience of radiotherapy (RT) as adjuvant treatment of histology confirmed pigmented villonodular synovitis ( PVNS)

We identified 13 patients ( 5 men  and 8 women ) with diffuse PVNS of the knee who were treated with postoperative RT between 2014-2021 at Radiotherapy and chemical center  in  Tishreen University Hospital in Lattakia , Syria. The median patient age was  35  ( range : 18 – 60 ) years. The median period for starting radiotherapy after surgery was 5.1 weeks
( range : 0.5-12 ) weeks.

 All patients received hypo-fractionated  external-beam radiotherapy using 3-dimensional conformal techniques. The radiation dose delivered in two phases :  the whole joint  25Gy
( 10 fractions of  2.5Gy  ) .

The median follow-up period was 2.7 ( range , 0.5 – 5 ) years. Of the 13 patients , 12 had  stable disease or were free of disease , clinically or on MRI imaging of the affected joint. 1 patients had local recurrence based on MRI imaging. None had acute or long-term complications from RT.

In conclusion , local radiotherapy should be considered for patients with PVNS, in cases of  extensive disease with incomplete excision and / or local recurrence.

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Published

2023-03-22

How to Cite

1.
سعد ب. The Hypo-fractionated Radiotherapy in the Management of Pigmented Villonodular Synovitis. One center experience . Tuj-hlth [Internet]. 2023Mar.22 [cited 2024May3];45(1):11-7. Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/13964

Issue

Vol. 45 No. 1 (2023): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

Section

Articles

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