مقارنة فعالية ديكلوفيناك الصوديوم مع ديكساميتازون فوسفات موضعيا ًكمضاد التهاب بعد عمليات الساد
Abstract
شملت الدراسة 30 مريضاً خضعوا لجراحة استخراج ساد خارج المحفظة مع زرع عدسة بيت خلفي وذلك في مشفى الأسد الجامعي باللاذقية لدراسة تأثير ديكلوفيناك الصوديوم 0.1% كبديل للديكساميتازون فوسفات 0.1% موضعياً لعلاج الالتهاب بعد العمل الجراحي, تم تقسيم المرضى بالتساوي إلى مجموعتين . كان المرضى في كلا المجموعتين متساوين بالمقاييس الأساسية, وتم تقييم احتقان الملتحمة, وذمة القرنية, شدة ارتكاس البيت الأمامي, والضغط داخل العين ومقارنتها في الأيام 1,3,7,21,42.
لم تظهر الدراسة فارقاً إحصائياً في التأثير العلاجي في كلا المجموعتين (p<0.05) و لم تلاحظ مضاعفات مهمة في كلا المجموعتين, يعد الديكوفيناك الموضعي بفعالية الديكساميتازون نفسها ويمكن استخدامه بشكل آمن في العلاج الروتيني للالتهاب بعد عمليات الساد غير المختلطة .
The study included 30 patients who had undergone ECCE-PCIOL surgery at Al- Assad University Hospital to study the effect of topical diclofenac sodium 0.1% as alternative to topical dexamethason phosphate 0.1% for treatment of postoperative inflammation. The patients were equally divided. Both groups were similar in baseline parameters. Severity of anterior chamber reaction (AC-reaction), corneal oedema, conjunctival injection and IOP were evaluated and compared on days 1, 3, 7, 21 and 42. The two groups did not differ statistically in treatment effect for any of the variables (p<0.05). No significant complication was seen in the two groups. Topical diclofenac is as effective as topical dexamethason and can be used safely in routin postoperative treatment following uncomplicated surgery.
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