دور البروجسترون في الوقاية من الولادة الباكرة

Authors

  • رئيفة مرعي
  • عصام الدالي
  • هزار الحسن

Abstract

الهدف من الدراسة: تقييم فعالية 17- هيدروكسي بروجسترون كابروات (OHPC -17) في خفض معدلات الولادة الباكرة في الحوامل عاليات الخطورة ممن لديهن قصة ولادة باكرة سابقة .

شملت الدراسة  80 حامل ممن لديهن قصة ولادة باكرة سابقة، تم تقسيمهم إلى مجموعتين :

المجموعةالأولى: ضمت 50 حامل تم إعطاؤهن حقن البروجسترون 250 ملغ أسبوعياً بدءاً من عمر
( 16-20) أسبوع وحتى بلوغ (36 )أسبوع أو حتى الولادة.

المجموعة الثانية: ضمت  30 حامل لم يعطين الدواء.

فوجدنا انخفاض واضح في معدل حدوث نكس الولادة الباكرة في المجموعة الأولى 28% مقارنة بالمجموعة الثانية 43.3%.

كما أن الانخفاض في معدل حدوث نكس الولادة الباكرة تم ملاحظته بعمر حملي أقل من(32.35.37) أسبوع في المجموعة الأولى (28%, 14%, 6%) مقارنة بالمجموعة الثانية (43.3%، 23.3%، 13.3%) على الترتيب.

The objective of this study is to evaluate the effectiveness of prophylactic use of
17- OHPC in preventing recurrent preterm delivery  in women with  a documented history of a previous spontaneous preterm birth. This study includes 80 pregnant women divided into two groups: The first includes 50 pregnant women receiving weekly  17- OHPC injections (250mg) from( 16-20) weeks up to 36weeks or delivery. The second group included 30 pregnant women receiving progesterone. We find that the recurrence of preterm birth is significantly less for women treated with17- OHPC (28%) compared to those (43.3%)who have not been treated. Women in the second group are significantly more likely to have spontaneous recurrent preterm birth at( <37,<35,<32) weeks of gestation (43.3%,23.3%,13.3%) compared to women who receive progesterone
( 28%,14%, 28%).

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Published

2019-01-17

How to Cite

1.
مرعي ر, الدالي ع, الحسن ه. دور البروجسترون في الوقاية من الولادة الباكرة. Tuj-hlth [Internet]. 2019Jan.17 [cited 2024May1];31(3). Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/6640

Issue

Vol. 31 No. 3 (2009): العلوم الصحية

Section

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