التقران السفعي دراسة وبائية إحصائية
Abstract
تبين هذه الدراسة معدل شيوع التقران السفعي لدى عينة من مراجعي العيادات الخارجية في مشفى الأسد الجامعي في مدينة اللاذقية بعمر 45 سنة فما فوق وذلك بين عامي 2008 و 2009 . قمنا في هذه الدراسة أيضاً بتحديد أهمية العوامل المؤهبة (مثل العمر, الجنس, ونمط الجلد) بالإضافة إلى العوامل البيئية والمهنية في تطور التقران السفعي. كان عدد أشخاص العينة 944 مريضاً (501 رجلاً و 443 امرأة). وجدنا أن المعدل الكلي لشيوع التقران السفعي كان 70.5% لدى الرجال و 29.5% لدى النساء, كما لاحظنا أن معدل الشيوع كان مرتبطاً بشكل وثيق بالعمر لدى كلا الجنسين, إذ بلغ 33.3% لدى الرجال و 20.6% لدى النساء بعمر 75 سنة فما فوق. لاحظنا وجود علاقة قوية لشيوع التقران السفعي مع علامتين ناجمتين عن التعرض للشمس هما درجة المران الشمسي ووجود الشامات الشيخية الشمسية. وكان معدل شيوع التقران السفعي أعلى لدى الأشخاص ذوي النمط اللوني I . لاحظنا أيضاً وجود معدل عالٍ للتقران الزهمي لدى كلا الجنسين, والذي يعدّ من الحالات المرتبطة بالعمر. لاحظنا في هذه الدراسة أن معدل شيوع التقران السفعي يزداد في المهن التي تتطلب التعرض للشمس لفترات طويلة (مثل الزراعة والأعمال الميدانية). سجلنا حالتي سرطان قاعدي الخلايا و4 حالات سرطان شائك الخلايا وحالتي قرن جلدي وحالة شوكوم قرني عند مرضى الدراسة.
This study examines the prevalence of sun-related damage to skin in people aged 45 and above attending outpatient clinics at Al-Assad University Hospital in Lattakia over the period October 2008 and October 2009. The importance of constitutional factors (complexion, skin type, age), as well as environmental and occupational exposures to the development of actinic keratosis (AK) was assessed in this study. Nine hundred and forty-four patients (501 men and 443 women) were recruited. The overall prevalence of AK was 70.5% in men and 29.5% in women. The prevalence was strongly related to age in both sexes, being 33.3% and 20.6%, respectively, in men and women aged 75 years and above, and was most strongly related to two objective signs of sun exposure, namely the degree of solar elastosis and the presence of solar lentigines. The prevalence of AK was higher in subjects with skin phototype I. There was a high prevalence of seborrhoeic keratosis in both sexes, which was an age-related case. Two cases of basal cell carcinoma, four cases of squamous cell carcinoma, one case of cutaneous horn, and one case of keratoacanthoma were identified.
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