A comparative study between tramadol and fentanyl in spinal anesthesia in cesarean section

Authors

  • Abd AlHadi Salama
  • Taysir Ibrahim
  • Saleh Karam

Abstract

Study Objective: Studying the efficacy of adding tramadol to spinal anesthesics for postoperative analgesia.

Setting: This study was carried out in the department of anesthesia and reanimation at Tishreen University Hospital, Lattakia, Syria during 2015-2016.

Patients: The study included 75 patients classified ASA I and  II, and were scheduled for elective cesarean section under spinal anesthesia.

Interventions: Patients were randomly divided into 3 groups (25 in each group):

Patients of group (A) received 12.5 mg bupivacaine 0.5% (3ml) + 25 μg fentanyl (½ml)

Patients of group (B) received 12.5 mg bupivacaine 0.5% (3ml) + 25 mg tramadol (½ml)

Patients of group (C) received 12.5 mg bupivacaine 0.5% (3ml) + normal saline (½ml)

Pain relief duration of each group, side effects, Blood pressure, heart rate and O2 saturation, were recorded.

Results: Analgesia duration was greatly prolonged in Tramadol group, and side effects were significantly lower than Fentanyl group.

Conclusion: 25 mg of intrathecal tramadol with bupivacaine cause a prolonged analgesia duration with no significant side effects.

دراسة مقارنة بين الترامادول والفنتانيل في التخدير الشوكي في العملية القيصرية

هدف الدراسة: دراسة فعالية مشاركة الترامادول مع أدوية التخدير الشوكي في التسكين بعد العمل الجراحي.

مكان الدراسة: أجريت هذه الدراسة في قسم التخدير والإنعاش في مشفى تشرين الجامعي - اللاذقية - سورية خلال عامي 2015 - 2016.

عينة البحث: شملت الدراسة 75 مريضة من مراجعي مشفى تشرين لإجراء عملية قيصرية انتخابية تحت التخدير الشوكي ينتمون إلى الصنف I و II حسب تصنيف ASA .

طريقة ومواد البحث: تم توزيع المرضى عشوائياً إلى 3 مجموعات (25 في كل مجموعة):

عند مرضى المجموعة (A) تم حقن 12.5 ملغ بوبيفاكائين 0.5% (2.5 مل) + 25 مكغ فنتانيل (½مل)

عند مرضى المجموعة (B) تم حقن 12.5 ملغ بوبيفاكائين 0.5% (2.5 مل) + 25 ملغ ترامادول (½مل)

عند مرضى المجموعة (C) تم حقن 12.5 ملغ بوبيفاكائين 0.5% (2.5 مل) +  نورمال سالين (½مل)

تم تسجيل فترة التسكين الخاصة بكل مجموعة، الآثار الجانبية، ضغط الدم، معدل النبض والإشباع الأوكسجيني.

نتائج الدراسة: فترة التسكين كانت أطول بشكل كبير لدى مرضى مجموعة الترامادول، والآثار الجانبية المسجلة كانت بنسبة أقل من مجموعة الفنتانيل.

الخلاصة: الترامادول داخل القراب بجرعة 25 ملغ مع البوبيفاكائين يسبب إطالة مدة التسكين بدون إحداث تأثيرات جانبية مهمة.

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Published

2018-09-09

How to Cite

1.
Salama AA, Ibrahim T, Karam S. A comparative study between tramadol and fentanyl in spinal anesthesia in cesarean section. Tuj-hlth [Internet]. 2018Sep.9 [cited 2024Nov.24];39(3). Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/3876

Issue

Vol. 39 No. 3 (2017): العلوم الصحية

Section

Articles

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