The Effect Of Nigella Sativa Oil On Induced Hypothyroidism In White Mice

Authors

  • Hiam Kamel Fadel Tishreen University
  • Hla Yaseen Hassan Tishreen University

Abstract

This study aimed to determine The effect of  Nigella sativa oil seeds on levels of FT3,FT4,TSH in the blood serum of  White adult mice of induced hypothyroidism and evaluates it's therapeutic influence.

This study included 30 female  white mice ( Balb/c strain ) which were divided into three experimental group .10 mice in each .the first group was the physiological control  treated orally with 0,9% Nacl until the end of the experiment. the second group was the pathological control treated orally with methimazole in dose of (0,05mg/kg) for three weeks and the third group was treatment group treated orally with 1ml/kg of Nigella Sativa oil for 4 weeks .at the end of experiment e blood simples were collected for biochemical analysis.

Result showed that the  oil of nigella sativa seeds has positive effect on hypothyroidism since the level of FT3, FT4 were significantly increase (p<0.05) ,moreover significantly decreas (p<0.05) in level  TSH was recorded.

Author Biographies

Hiam Kamel Fadel, Tishreen University

Professor-Department Of Zoology-Faculty of science

Hla Yaseen Hassan , Tishreen University

Master Student –Department of Zoology – Faculty of science

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Published

2021-11-08

How to Cite

فاضل ه. . ك. ., & حسن ح. ي. . (2021). The Effect Of Nigella Sativa Oil On Induced Hypothyroidism In White Mice. Tishreen University Journal -Biological Sciences Series, 43(5). Retrieved from https://journal.tishreen.edu.sy/index.php/bioscnc/article/view/11067

Issue

Vol. 43 No. 5 (2021): Tishreen University Journal for Research and Scientific Studies - Biological Sciences Series

Section

Master student researches

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