إنتان الدم عند الوليد دراسة التشخيص المخبري والمعالجة بالمضادات الحيوية
Abstract
دراسة شملت 56 حالة إنتان دم مثبت عند الوليد وزعت على مجموعتين , الأولى تضم 25 وليدا بعمر دون 24 ساعة, والأخرى تضم 31 وليدا بعمر 1ـ28 يوما.
تمت دراسة حساسية الاختبارات الكيميائية والجرثومية وتأثير الصادات الحيوية على المجموعتين, ففي المجموعة الأولى عزل 25جرثوما وكان إيجابي الغرام في 84% من الحالات ونسبة الحساسية على الأمبيسيللين 88% من الحالات.أما في المجموعة الثانية فعزل 31 حالة أيضا كان سلبي الغرام في77,5% من الحالات و 77% منها كانت حساسة على السيفوتاكسيم. ووجد أن الاختبارات الجرثومية التي شملت رشافة المعدة, وزرع البراز ذات حساسية أفضل من الاختبارات الكيميائية الحيوية الباكرة كالبروتين الارتكاسي(CRP) C.
The records of 46 neonates proven septicemia were retrospectively studied. Patients could be divided in 2 groups: in group 1 (25 infants) a positive blood culture was obtained before one day of life; in group 2 (31 infants) a positive blood culture was obtained between day 1 and 28. The sensitivity of available chemical and bacteriological tests and the efficacy of the initial antibiotic treatment were examined in both groups. Of the 25 germs isolated in patients from group 1; 84% were gram positive bacteria and 88% were susceptible to ampicillin. Of the 26 germs isolated in patients from group 2; 77.5% were susceptible to cefotaxime. Bacterial tests (gastric aspiration, feces culture) had a better sensitivity than early biochemical tests (C reactive protein ).
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