Antibacterial and Antioxidant Activity of Essential Oil of Wild Ruta Chalepensis

Authors

  • Muhammad al-Kurdi Damascus University
  • Ahmad Kara Ali Tishreen University
  • Boushra Ali Damascus University

Abstract

Leaves of wild Ruta chalpensis were collected from Salib al-Turkman in Lattakia. Essential oil of dried leaves was isolated using Clevenger; Methanolic extract was prepared using Soxhlet extractor. The antibacterial activity of extracted essential oil was tested against Gram-positive bacteria such as Staphylococcus aureus and Gram-negative bacteria such as Escherichia coli, Pseudomonas aeruginosa , and Klebsiella. Essential oil showed a very high sensitivity against Klebsiella, a high sensitivity against S. aureus and P. aeruginosa, and a good sensitive against E.coli.  

Antioxidant activity of methanolic extract and essential oil of Ruta chalepensis was characterized using 1, 1,-diphenyl-2- picrylhydrazyl (DPPH) radical scavenging assay. The IC50 was (0.091 mg/ml) for methanolic extract and (0.071 mg/ml) for essential oil, this means that the methanolic extract has more antioxidant than essential oil.

 

Author Biographies

Muhammad al-Kurdi, Damascus University

Professor, Faculty of Science Chemistry

Ahmad Kara Ali, Tishreen University

Professor, High Institute of Marine Research, Marine Chemistry Department,

Boushra Ali, Damascus University

PhD. Student, Faculty of Science

Published

2021-05-20

How to Cite

1.
الكردي م, قره علي ا, علي ب. Antibacterial and Antioxidant Activity of Essential Oil of Wild Ruta Chalepensis. TUJ-BA [Internet]. 2021May20 [cited 2024Nov.24];43(2). Available from: https://journal.tishreen.edu.sy/index.php/bassnc/article/view/10546