Comparison of ethanolic extract of garlic with Glibenclamide on some biochemical standards in mice which diabetic mellitus

Authors

  • Hiam Fadel Tishreen University
  • Mofeed Yaseen Tishreen University
  • Kholoud Sheikh Yousef Tishreen University

Abstract

This study aimed to determine the effect of ethanolic extract of Allium sativums on the levels of glucose ,cholesterol and triglyceride in the blood serum of adult white mice with induced diabetes.

This study included 40 male mice of Balb/c, which were divided into four experimental groups (10 mice per group).

The results showed a significant increase (P <0.05) in the concentration of glucose, cholesterol and triglycerides in the blood serum of the group of mice injected with alloxan compared with the physiological control, and the results also showed a significant decrease

 (P <0.05) in the concentration of glucose, cholesterol and triglycerides in the blood serum of the group of mice. Treatment with garlic compared to control glucose.

Results showed that ethanolic extract of Allium sativums has an important effect on lowering the level of  biochemical to normal values equivalent to Glibenclamide.

Author Biographies

Hiam Fadel, Tishreen University

Professor-Department Of Zoology-Faculty of science

Mofeed Yaseen, Tishreen University

Professor –Department of analytical chemistry- Faculty of pharmacy

Kholoud Sheikh Yousef, Tishreen University

phd Student –Department of Zoology – Faculty of science

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Published

2021-05-30

How to Cite

فاضل ه. ., ياسين م. ., & شيخ يوسف خ. . (2021). Comparison of ethanolic extract of garlic with Glibenclamide on some biochemical standards in mice which diabetic mellitus. Tishreen University Journal -Biological Sciences Series, 43(2). Retrieved from https://journal.tishreen.edu.sy/index.php/bioscnc/article/view/10580

Issue

Vol. 43 No. 2 (2021): Tishreen University Journal for Research and Scientific Studies - Biological Sciences Series

Section

Articles

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