تصليب القرنية الضوئي في علاج اعتلال القرنية الفقاعي
Abstract
الهدف: دراسة تأثير تصليب القرنية على اعتلال القرنية الفقاعي المحدث بالعدسات الصنعية
الطرق: شارك بالدراسة 15مريض مشخص لديهم اعتلال قرنية فقاعي تالي لاستئصال الساد و زرع عدسات داخل العين. تم إجراء فحص القدرة البصرية المصححة ,الفحص بالمصباح الشقي , تقدير شفافية القرنية و الألم العيني و قياس سماكة القرنية قبل التصليب و بعد شهر, 3 أشهر, 6 أشهر من التصليب.
تم اجراء تصليب القرنية بعد إزالة الظهارة و تقطير الريبوفلافين كل 3 دقائق لمدة نصف ساعة ثم تطبيق الاشعة فوق البنفسجية A لمدة نصف ساعة مع تطبيق الريبوفلافين كل 5 دقائق.
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النتائج: كان العمر الوسطي للمرضى 65.5 سنة (9 اناث و 6 ذكور). حدث تناقص ملحوظ بسماكة القرنية بعد التصليب و لم يكن هناك تغير هام بالقدرة البصرية بعد التصليب. حصل تحسن في شفافية القرنية بالشهر الأول فقط. تناقص الالم العيني بشكل ملحوظ بعد التصليب خاصة بالشهر الأول و الثالث.
الاستنتاج: تصليب القرنية الضوئي اجراء فعال و مؤقت لتخفيف الألم العيني لدى مرضى اعتلال القرنية الفقاعي.
Aim: To study the efficacy of collagen crosslinking on pseudophakic bullous keratopathy.
Methods: Fifteen patients with pseudophakic bullous keratopathy participated in the study. Corrected visual acuity measurement, slit lamp examination, corneal clarity grading, ocular pain intensity scale and corneal thickness measurement were performed before corneal crosslinking and 1, 3 and 6month postcrosslinking. Corneal collagen crosslinking was performed after the removal of the epithelium and the application of riboflavin every 3 minutes for 30 minutes then the ultraviolet irradiation applied for 30 minutes with the application of riboflavin every 5 minutes.
Results: The mean age was 65.5 year (9 females and 6 males). Corneal thickness decreased significantly after crosslinking but the visual acuity did not change significantly after crosslinking. Corneal transparency improved in the first month. Ocular pain decreased significantly in the first and third month.
Conclusion: Corneal collagen cross linking is an effective and temporal procedure to decrease ocular pain for bullous keratopathy patients
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