Using Albumin Denaturation Inhibition Method to Determine the Anti-Inflammatory Activity of Phenolic Compounds in Some Locally Available Fruit Juices

Authors

  • Dima Al Diab Tishreen University
  • Nouma Hasan Tishreen University
  • Akram Nezam Tishreen University

Abstract

Fruit Juices are considered as an important source of phenolic compounds. Three natural Black mulberry, Pomegranate and orange juices were selected to determine their phenolic content and assess their anti-inflammatory activity. A phenolic extract for each juice was also prepared. Total Phenolic content was determined using Folin-Ciocalteu method. The anti-inflammatory activity was evaluated using albumin denaturation inhibition method at concentration of phenolic compounds ranged between (10- 60 µg/ml). Ibuprofen was used as a standard drug.

Phenolic content in juices was higher than their phenolic extracts. The highest total phenolic content was found in black mulberry juice and its phenolic extract. Black mulberry juice and its phenolic extract also revealed the highest anti-inflammatory activity among the studied juices. Phenolic extracts showed higher anti-inflammatory activity than the juices at the same concentration of phenolic compounds.

Author Biographies

Dima Al Diab, Tishreen University

Associate Professor - Analytical and Food Chemistry Department, Faculty of Pharmacy

Nouma Hasan, Tishreen University

Assistant Professor - Pharmacology and Toxicology Department, Faculty of Pharmacy

Akram Nezam, Tishreen University

Postgraduate Student (MSc) - Analytical and Food Chemistry Department, Faculty of Pharmacy

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Published

2021-03-09

How to Cite

1.
الدياب د, حسن ن, نظام أ. Using Albumin Denaturation Inhibition Method to Determine the Anti-Inflammatory Activity of Phenolic Compounds in Some Locally Available Fruit Juices. Tuj-hlth [Internet]. 2021Mar.9 [cited 2024Nov.24];43(1). Available from: https://journal.tishreen.edu.sy/index.php/hlthscnc/article/view/10425

Issue

Vol. 43 No. 1 (2021): Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

Section

Articles

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